This disease affects everyone differently. My problems are mostly mobility with my left leg. Mostly all my PD symptoms are on my left side. I also have bone on bone elbow arthritis in my left elbow which makes uncontrollable dyskinesia movements a lot of fun. I started using a cane. I've recently noticed a big decrease in my sense of smell and also more stalling-freezing while walking. This happens towards end of dose. I find that my first dose of pills in the morning-4 Rytary 95 and 1 Entacapone 200 is the best, I can almost function normally for 4 hours or so. Subsequent doses are not as effective. God forgive me if I have a Bacon, Egg and Cheese On a hard roll (standard New Jersey breakfast) before I dose. Protein destroys my PD medication. I can barely walk. Watch out for protein!!!!-especially bacon!