Azilect, Neupro patch, nausea

[jim.skier]

I started on 4mg patches of Neupro (1 week), working my way up from 4 hours/day to "round the clock". But I have had trouble using my prescribed patches (6 mg) because after several hours I feel nauseated. Anyone with experience that this symptom will lessen, allowing me to work my way up to "round the clock" as prescribed?

Also, my neurologist prescribed Azilect for it's possible neuro-protective qualities (to slow or stop progression of PD as well as alleviating some symptoms). Though he told to start that regimen (ironically, also 4 mg/day for 1 week, 6 mg/day thereafter), but only after getting used to the Neupro. Anyone with experience with Azilect, with or without Neupro?

[Roberta]

Can't help with Azilect but if you live in the USA, the Neupro patch cannot be dispensed after 30 April. My wife Roberta has been on the 6mg patch several months and it really helps with the pain in her legs. To combat the nausea we put the patch on at bed time ea evening. It is a 24 hour patch. If you are using it more often, that may account for some of the nausea. Good luck. Roberta

[susan wheatley]

hi jim, i am on the neurpo patches and have been on them for about 9months am currently on a 2mg and 8mg have not had any nausea at all just slight skin irritation. iam sure the nausea will settle down once your body gets used to the patches they seem to work for me iam also on madopar and selegiline this combination works for me hope thing s sort them selves out soon.

[parkie]

here in south africa azilect is not approved by the medical council and it may take a further 2 years before you can get it from the chemist. I know it is approved in the usa and europe. could somebody advise, do you have to go to a doctor, or can you buy it over the counter, if so how much does it cost, and who supplies it, thanks.

[MargieB]

here in south africa azilect is not approved by the medical council and it may take a further 2 years before you can get it from the chemist. I know it is approved in the usa and europe. could somebody advise, do you have to go to a doctor, or can you buy it over the counter, if so how much does it cost, and who supplies it, thanks.


Hi Parkie,

I wish I would know information about azilect so I could tell you the cost, supplier, etc. but I have an idea that might help. Do you have an American Counselate near where you live? If you do, maybe they would be able to give you this information. It's just a thought. I hope it turns out to be a positive one.

Margie :)

[tinkerbell]

hi jim.skier,

i take azilect also requip and sinemet plus, to cure the nausea i use those travel bands you put on your pulse on the wrist, they have done the trick for me.
tinkerbell

[suzie Q]

Re: caregiving

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hI eVERY ONE I HAD HUGE PROBLEMS ON ONE OF THE MEDICATIONS THAT i WAS TAKING FOR P.D( CABASAR ).I WAS GAMBLING BECAUSE THEY CAUSED ADDICTIVE BEHAVIOUR AND THEY ALSO CHANGED MY PERSONALITY I AM LUCKY THAT I HAVE A FAMILY THAT UNDERSTOOD THAT THIS WAS NOT REALLY ME AND WERE THERE FOR ME ...THANKFULLY THAT IS ALL IN THE PAST AND I AM OFF THEM NOW AND I HAVE MY OWN SELF BACK .IT WAS A REALLY BAD TIME THAT I THOUGHT WOULD NEVER END ,BUT I GOT THROUGH AND CAME OUT OK ........NOT TOO MUCH DAMAGE TO THE BANK ACCOUNT. LOL ..

SUE



THIS MAY BE IN THE WRONG SECTION .......HERE IT IS ANYWAY
HEATHER SUGGESTED I POST THIS IN MEDICATIONS I HAD IT IN CAREGIVER SECTION CAUSE SOME ONE TALKED ABOUT COMPULSIVE BEHAVIOUR
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Last edited by suzie Q : Today at 01:55 PM.

[Scott K]

Hello.

I have found Azilect to be very helpful. For me it has made a dramatic difference.

I was diagnosed with PD in the summer of 05 and started on Levadopa and Requip. Azilect was approved in the US in the summer of 06 as I recall.

In Dec. 06, I happened to read something about it by chance and mentioned to my doc that I would like to try it. Within weeks I noticed a significant reduction in the symptoms I was experiencing like soreness in my shoulder, stiff neck, facial twitching etc.

From what I read Azilect was supposed to help with symptoms and slow the onset of PD by 45% by helping slow the depletion of dopamine. That being the case, after being on .5mg for azilect for 6mo, I asked the doc to increase me to the max allowable - 1mg (once a day). The 18 months I have been on it, I have been relatively symptom free.

I don't know why more docs aren't suggesting this for their patients, so if your doc hasn't mentioned it, you might want to bring it up yourself. My doc was reluctant (new drug and all that) but thankfully he supported my request to try it.

p.s. as I mentined I also take requip. My doc started me on 1/2 mg of requip 3xday soon after being diagnosed. Within 6mo. the doc increased it to 1mg 3xday. That increase caused severe mental issues like forgetfulness, confusion, indecision, and a general spaced out feeling. After 3mos. or so, I went back to .5mg 3xday and have not had those wierd problems.

[heather]

Hi Scott K
http://i10.photobucket.com/albums/a126/maesisaf/welhandwel.gif

I'm Heather and a carer for my husband
I haven't heard of Azilect, you say it was only licensed2006, do you no if it's licensed in the UK
have you experienced any side affects from it
do you mind if i ask how long you have been diagnosed with PD
take care and keep well

[tinkerbell]

hi heather,

i have been on azilect since being diagnosed in august 2006 i have had no side effects from it at all.

tinkerbell

[heather]

Hi Tinker bell

I haven't heard of this,but then i then i haven't heard of most of them
Is it used for stiffness?

Jim is quickly seizing/ stiffening up,he can't move his head to even say yes or no
I have to jerk his arm's to dress and undress him, [they are bent at the elbow]
his hands are clawing,so he can't hold a spoon etc
and between his neck and shoulders are stiff

[Filo]

Hi, first time here and replying to a couple of questions - not sure if that is the correct thing to do?

Have had PD since age 5, and Sinemt Plus since age 20 or so, I am forty now.

No real problems till about a year or so ago, now taking Azilect once a day. Stalevo 100 every 3 hours, six times a day, and Neupro patches 12mg every day. Madopar disperible 2x as required (mostly during the night time)

Azilect wonderful no problems

Stalevo - much better than just Sinemet

Neupro - works but makes me unwell, until get used to it

Madopar - a life saver

Still reviewing sitution as problems continuing and getting better.

thanks

[Drew Saunders]

Hi to everyone this very rainy Tuesday.
As previously mentioned I take 9 sinemet 62.5 per day. Basically 2 at 8.00am and 1 every 2 hours up to 10.00pm. I was finding that my tremors were starting before I was due the next med so my consultant gave me Azelect 1mg to take once per day which I take with my first 2 sinemet of the day and now (as long as I remember to take the sinemet at the correct time - I have a timer but don't always remember where I left it!) I have no tremor unless of course I get stressed out by whatever.
Hope this helps
Hope you are all having the best day that you can,
Kindest Regards
Drew

[Drew Saunders]

Hi, first time here and replying to a couple of questions - not sure if that is the correct thing to do?

Have had PD since age 5, and Sinemt Plus since age 20 or so, I am forty now.

No real problems till about a year or so ago, now taking Azilect once a day. Stalevo 100 every 3 hours, six times a day, and Neupro patches 12mg every day. Madopar disperible 2x as required (mostly during the night time)

Azilect wonderful no problems


Stalevo - much better than just Sinemet

Neupro - works but makes me unwell, until get used to it

Madopar - a life saver

Still reviewing sitution as problems continuing and getting better.

thanks

Filo, I am amazed. You say you have had PD from the age of 5? Amazing. With regards being on the straight and narrow for a long time and then suddenly things go down hill I'm afraid that is the way of PD. What I would advise you NOT to do is dwell on this and worry about when the next drop will occur. Live for today and have the best time that you can and of course find the funny things in life and have a good laugh - the best medicine of all, Kindest Regards,
Drew

[heather]

Hi to everyone this very rainy Tuesday.
As previously mentioned I take 9 sinemet 62.5 per day. Basically 2 at 8.00am and 1 every 2 hours up to 10.00pm. I was finding that my tremors were starting before I was due the next med so my consultant gave me Azelect 1mg to take once per day which I take with my first 2 sinemet of the day and now (as long as I remember to take the sinemet at the correct time - I have a timer but don't always remember where I left it!) I have no tremor unless of course I get stressed out by whatever.
Hope this helps
Hope you are all having the best day that you can,
Kindest Regards
Drew

Hi Drew
hope you are well we have a sunny Tuesday, good old Wales

missed you

[heather]

Hi, first time here and replying to a couple of questions - not sure if that is the correct thing to do?

Have had PD since age 5, and Sinemt Plus since age 20 or so, I am forty now.

No real problems till about a year or so ago, now taking Azilect once a day. Stalevo 100 every 3 hours, six times a day, and Neupro patches 12mg every day. Madopar disperible 2x as required (mostly during the night time)

Azilect wonderful no problems

Stalevo - much better than just Sinemet

Neupro - works but makes me unwell, until get used to it

Madopar - a life saver

Still reviewing sitution as problems continuing and getting better.

thanks

hi Filo
You will soon find your way around, feel free to answer anywhere and start whatever you want
look forward to chatting more

[heatherwilmot]

Hi Drew
hope you are well we have a sunny Tuesday, good old Wales

missed you
From Heather (P)

Evening, bright sunny one. 5 pm. Had to write and thank you for all the informaton re Sinemet. When you all chat many items of great help come to light, I guess that is where such a Forum comes into its own, should be most helpful. Timing is something I just cannot get right, I only learnt recently that too soon or too late will not do! I will have to get a timer-watch. things are slowly getting better. Good luck to you all, Heather(P)

[Drew Saunders]

From Heather (P)

Evening, bright sunny one. 5 pm. Had to write and thank you for all the informaton re Sinemet. When you all chat many items of great help come to light, I guess that is where such a Forum comes into its own, should be most helpful. Timing is something I just cannot get right, I only learnt recently that too soon or too late will not do! I will have to get a timer-watch. things are slowly getting better. Good luck to you all, Heather(P)

Hi Heather
Not quite sure but I think if you contact local chapter of PD they can give details of timer pill box.
Hey - the sun in shining in glorious Leicestershire.
Hope you and Jim are havin' a good day,
Drew

[Reisa]

I am new to this site so I apologize if I am writing in the wrong place or bringing up too many topics at once. I also don't really understand how a forum works. I would be happy to have someone explain it to me.

My husband was diagnosed with PD in June 2007 and just started taking medication a few weeks ago. He went on Azilect .5mg as we had heard that it possibly slows the progress of the disease. We have been charting his symptoms on a scale of 1-10 since the first day he took it. He is also on Remeron for sleeping and anti-anxiety or depression (though it is one of the meds that is contraindicated his psychiatrist said he could take it as the dose he is taking of remeron is small). On the third day he took Azilect, he was very excited as he thought his rigidity had lessened and that his movement was quicker and easier but since then there has been little if any improvement at all. In fact I think he is more exhausted than he has ever been. I know I must be patient and that he may have to increase his dose for it to have any effect. Is there anyone who has taken Azilect alone as monotherapy who has had definitive positive results in reducing symptoms and improving health; if so which symptoms have been positively affected?

What are the scary side effects that people have been referring to about azilect?

Why are neurologists not prescribing azilect when it may actually slow the progress of the disease?

My husband refuses to do exercises which I have seen him do for a week just after he saw the physiotherapist. I witnessed how a week of continuous exercises helped improve his posture and his mobility. Any ideas of how to get him to do these exercises (suggested by a physio in the PD clinic) without me nagging? I am convinced exercise has a huge benefit but he seems to resist whatever I suggest.

Has anyone been dancing or doing tandem biking or drumming or playing piano or singing? I am also convinced that doing an activiity that requires rhythm helps someone with Parkinson's. Any experiences to support this concept?

Reisa

[suzie Q]

Hi Reisa

I cant answer your questions about medication but i play the piano and love it .It keeps my fingers moving sometimes when my meds not working i hit the wrong keys but most of the time it is ok.I also bought myself a wii it is a nintendo game console thta i read was very good for p.d google it .I find this a fun wary to excercise .i am 53 and have had p.d 5 years .i live in Tasmania Australia

hope to talk some more

sue

[Gail]

Hi Reisa,

i am a big believer that exercise keeps me moving. i try to get some exercise everyday, and really feel the difference on the days i don't. I had read that walking on a treadmill is very good for keepin us walking with a good gait, so i do that at least 4 times a week and i believe it does help. i am 53 and was diagnosed about 3 1/2 years ago.


gail

[Pauline]

HiReisa
I don't take Azilect
But I had heard it slow the progresion of PD , so I asked my PD specialist and she told me it is not conclusive that it slows it down, and she told me it was ver mild so would not work for me Exercise is very good But I don't know how you can motivate your hubby I know with the exhaution you feel, it is very hard to get your self going . Ask you Pharmist and they should be able to give you a print out of the side effects of the medications your husband is on Ask your Dr to explain the menifits of exercise maybe he will listen to him :):):)Pauline